Provided herein are immunoconjugates comprising an anti-ROR1 antibody or an antigen-fragment fragment thereof and a drug moiety. These immunoconjugates are useful for treating ROR1 expressing cancers.本文提供一種免疫接合物,其包含抗ROR1抗體或其抗原片段片段及藥物部分體。此等免疫接合物適用於治療表現ROR1之癌症。