A pre-packaged medical device includes a tray supporting a medical device such as a blood collection set including a needle assembly and a tube holder. The tray defines a first contoured portion supporting at least a portion of the needle assembly and a second contoured portion supporting the tube holder. The tray may have a tray body with a plurality of posts upstanding from a bottom wall in the first contoured portion for engaging the needle assembly. The posts may be positioned to maintain the needle assembly in a defined orientation while preventing the inadvertent actuation of the needle assembly, which may include a spring-driven safety shield. The configuration of the pre-packaged medical device allows sequential removal of the blood collection set, typically in the order of intended use including first removal of a needle assembly, second removal of tubing, and third removal of the tube holder.
