A medical manipulator comprises a distal end working unit includinga gripper as an end effector, an operating unit for operating the distal endworkingunit, a coupling interconnecting the distal end working unit and the operatingunit,and an attitude changing mechanism for changing an attitude of the distal endworking unit. When the operating unit is operated by an operator, the endeffectoris mechanically operated by a transmitting member. The attitude changingmechanism is operated by a bending drive source and a rotational drive source,which are operated when the operating unit is operated by the operator.
