Michael Aaron Brodney,Elizabeth Mary Beck,Christopher Ryan Butler,Lei Zhang,Brian Thomas O'Neill,Gabriela Barreiro,Erik Alphie LaChapelle,Bruce Nelsen Rogers,Brian Thomas ONeill
申请号:
US15629215
公开号:
US20170304312A1
申请日:
2017.06.21
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I,and the variable R1 is as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.