BONVINI EZIO,JOHNSON LESLIE S,HUANG LING,MOORE PAUL A,CHICHILI GURUNADH REDDY,ALDERSON RALPH FROMAN
申请号:
AP2016009029
公开号:
AP2016009029A0
申请日:
2014.08.20
申请国别(地区):
AP
年份:
2016
代理人:
摘要:
The present invention is directed to sequence-optimized CD 123 x CD3 bi-specific monovalent diabodies that are capable of simultaneous binding to CD123 and CD3, and to the uses of such diabodies in the treatment of hematologic malignancies.