A medicament for treating upper respiratory mucosal congestion, the medicament having a combination of approximately 2-4 mg phenylephrine hydrochloride (or an equivalent amount of a pharmaceutically acceptable alternative form of phenylephrine); and approximately 250-500 mg paracetamol for providing an adult with a total dose of approximately 4-8 mg phenylephrine hydrochloride (or an equivalent amount of a pharmaceutically acceptable alternative form of phenylephrine) and approximately 500-1000mg paracetamol. Use of such a combination in the treatment of upper respiratory mucosal congestion is also disclosed.