Philip A. Eckhoff,Muriel Y. Ishikawa,Nels R. Peterson,Lowell L. Wood, JR.,Victoria Y. H. Wood
申请号:
US14167854
公开号:
US20150211950A1
申请日:
2014.01.29
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods, systems, and devices are described for calculating a push pressure for a pharmaceutical vial with a syringe, the method including accepting data regarding at least one parameter of the pharmaceutical vial, at least one parameter of a vial cap with a seal, at least one parameter of the syringe, and a single dose volume of a liquid pharmaceutical calculating a volume of headspace over the liquid pharmaceutical with a computing device calculating an ejection pressure based on the single dose volume of the liquid pharmaceutical and the volume of headspace calculating a motive pressure based on a static force and a cross-sectional area of the syringe defining the push pressure as the greater of the ejection pressure or the motive pressure and reporting the push pressure to a user. The method further includes calculating a molar amount of inert gas needed in the pharmaceutical vial to generate the calculated push pressure.