JOHNSON; RICHARD J.;JOHNSON, RICHARD J.;NAKAGAWA, TAKAHIKO
发明人:
JOHNSON, RICHARD J.,NAKAGAWA, TAKAHIKO
申请号:
EP09821384
公开号:
EP2398319A4
申请日:
2009.10.19
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Disclosed herein are compositions and methods for treating chronic kidney disease and/or a metabolic imbalance. Specifically exemplified herein are methods involving the coadministration of a RAS inhibitor with a conjunctive agent that improves endothelial NO or endothelial function. Also disclosed are methods of treating a patient exhibiting symptoms of a stage of chronic kidney disease and at least one symptom of a metabolic imbalance, such as one or more diagnostic criteria of the metabolic syndrome.