A ureteral access sheath (10) adapted for insertion into a urethra includes an elongate tube (14) extending between a proximal end, and a distal end. A handle (23) assembly is disposed at the proximal end, and includes enlarged portions which inhibit migration of the sheath into the urethra. The enlarged portion is shaped like the bell of a horn with a concave, distally facing outer surface (41), and a convex, proximally facing inner surface. The inner surface functions as a funnel while the outer surface is sized, and configured to receive adjacent fingers of a users hand held in its natural position. In an associated method, this shape of the handle assembly facilitates maintaining the sheath (10) in a stationary position during insertion, and removal of instrumentation. The handle assembly can be movable on the tube to facilitate variation of the sheath link in situ.