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METHODS OF TREATING A MEIOTIC KINESIN-ASSOCIATED DISEASE
专利权人:
发明人:
申请号:
EP09767337.0
公开号:
EP2315594B1
申请日:
2009.05.28
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The invention provides methods of treating a meiotic kinase-associated disease, preferably the meiotic kinase HSET, by administering an inhibitor of the meiotic kinase. Preferably, the disease is associated with the presence of supernumerary centrosomes, such as cancer. Methods of inhibiting the growth of a tumor cell by contacting the cell with an inhibitor of a meiotic kinase, preferably HSET, are also provided. Screening methods for identifying inhibitors of the meiotic kinase HSET are also provided. Methods of selecting subjects for treatment with an inhibitor of a meiotic kinase, such as HSET, are also provided.
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