A brake system for a patient support apparatus (2) having a base frame (12) includes pedals (34,36,44,46,48,50) positioned to be moved by a user to move a brake and a mechanism (32) positioned to coordinate movement of the pedals (34,36,44,46,48,50) so that downward movement of one pedal positioned adjacent the head end of the base (12) causes movement of the mechanism (32) in a first direction and downward movement of another of the pedals (34,36,44,46,48,50) causes movement of the mechanism (32) in a second direction, opposite the first direction.