Various embodiments for providing removable, pluggable and disposable opto-electronic modules for illumination and imaging for endoscopy or borescopy are provided for use with portable display devices. Generally, various rigid, flexible or expandable single use medical or industrial devices with an access channel, can include one or more solid state or other compact electro-optic illuminating elements located thereon. Additionally, such opto-electronic modules may include illuminating optics, imaging optics, and/or image capture devices, and airtight means for suction and delivery within the device. The illuminating elements may have different wavelengths and can be time-synchronized with an image sensor to illuminate an object for 2D and 3D imaging, or for certain diagnostic purposes.