Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
发明人:
ZHONG, Wu,YANG, Meiyan,GONG, Wei,WANG, Yuli,GAO, Chunsheng,ZHOU, Xinbo,LI, Song
申请号:
EP17826907
公开号:
EP3485886A4
申请日:
2017.07.04
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a pharmaceutical composition, comprising Tecovirimat, cyclodextrin and an additive, and optionally a pharmaceutically acceptable excipient. The present invention also relates to a method for preparing the pharmaceutical composition. The composition improves the solubility of Tecovirimat in water by using cyclodextrin and meglumine in combination, as compared with the solubility of Tecovirimat in water by using cyclodextrin or meglumine alone.