KANG STEM BIOTECH CO.; LTD.;康干细胞生物技术有限公司;KANG STEM BIOTECH CO., LTD.;康幹細胞生物技術有限公司
发明人:
康景宣,俞炅录,俞炅錄
申请号：
MOJ001870
公开号：
MOJ001870B
申请日:
2015.09.10
申请国别(地区):
MO
年份:
2017
代理人:
摘要：
The present invention relates to the methods for obtaining adult stem cell from the cell origin comprising stem cell with what, wherein the adult stem cell has surface antigen CD49f, it is formed by what sphere and forms sphere and high expression OCT4 and SOX2 excellently, further relate to contain the adult stem cell obtained by this method or the cellular therapeutic agent from the cell of its differentiation as active constituent. According to the present invention, the adult stem cell of source what sphere is suitable for mass propgation adult stem cell, because it grows more rapidly compared with the stem cell obtained by known attachment cultural method, they have specific surface antigen, allow by using the specific surface antigen with quality obtain, and by what its it is good differentiation and can with what using its prepare cellular therapeutic agent.本發明涉及用於從包含幹細胞的細胞來源獲得成體幹細胞的方法，其中所述成體幹細胞具有表面抗原CD49f，由於球體形成而優良地形成球體以及高表達OCT4和SOX2的，還涉及含有通過該方法獲得的成體幹細胞或從其分化的細胞作爲活性成分的細胞治療劑。根據本發明，來源於球體的成體幹細胞適用於大量培養成體幹細胞，因爲其與由已知的附著培養方法獲得的幹細胞相比生長更快速，它們具有特定的表面抗原，使得通過使用該特定的表面抗原可以同質地獲得，並且由於其良好的分化而可用於利用其製備細胞治療劑。
