Joshua E. Allen,Wafik S. El-Deiry,Arun K. Sharma,Shantu G. Amin
申请号:
US14652363
公开号:
US20150328310A1
申请日:
2013.12.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compositions and methods for treating cancer in a subject in need thereof are provided according to aspects of the present disclosure which include both cetuximab and ISC-4, as a combination formulation or as separate formulations. Methods of treating cancer in a subject in need thereof are provided according to aspects of the present disclosure wherein the subject has cancer characterized by wild-type KRAS wherein the methods include administering a combination of cetuximab and ISC-4 as a combination formulation or separately, and wherein administration of the combination of cetuximab and ISC-4 provides a synergistic anti-cancer effect, treating the cancer.