The present invention relates to pharmaceutical formulations of anti-viral active agents for the use in topical application, particularly for the use of these in the treatment of human herpes virus infections, wherein the anti-viral active agents may be selected from the group comprising the N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)-phenyl]-acetamide free base hemihydrate, the maleate salt of N-[5-(amino-sulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide, the mesylate salt of N-[5-(amino-sulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide, and the free base of N-[5-(amino-sulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide.本發明係關於一種用於局部施用之抗病毒活性劑的醫藥調配物,特別係關於其用於治療人類疱疹病毒感染之用途,其中該等抗病毒活性劑可選自包括以下之群:N-[5-(胺基磺醯基)-4-甲基-1,3-噻唑-2-基]-N-甲基-2-[4-(2-吡啶基)-苯基]-乙醯胺游離鹼半水合物、N-[5-(胺基-磺醯基)-4-甲基-1,3-噻唑-2-基]-N-甲基-2-[4-(2-吡啶基)苯基]乙醯胺之馬來酸鹽、N-[5-(胺基-磺醯基)-4-甲基-1,3-噻唑-2-基]-N-甲基-2-[4-(2-吡啶基)苯基]乙醯胺之甲磺酸鹽及N-[5-(胺基-磺醯基)-4-甲基-1,3-噻唑-2-基]-N-甲基-2-[4-(2-吡啶基)苯基]乙醯胺之游離鹼。
