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salts of a pim kinase inhibitor
专利权人:
INCYTE CORPORATION
发明人:
CHANGSHENG ZHENG,CHONGSHENG ERIC SHI,GANFENG CAO,JIACHENG ZHOU,LEI QIAO,MICHAEL XIA,QIYAN LIN,QUN LI,VAQAR SHARIEF,YOUNGCHUN PAN,ZHONGJIANG JIA
申请号:
BR112018004596
公开号:
BR112018004596A2
申请日:
2016.09.09
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention relates to salt forms of the n - {(7r) -4 - [(3r, 4r, 5s) -3-amino-4-hydroxy-5-methylpiperidin-1-yl] -7 pim kinase inhibitor -hydroxy-6,7-dihydro-5h-cyclopenta [b] pyridin-3-yl} -6- (2,6-difluorophenyl) -5-fluoropyridine-2-carboxamide, including methods for preparing the same , and intermediates in the preparation thereof, wherein the compound is useful in treating pim kinase-related diseases such as cancer.a presente invenção se refere a formas de sal do inibidor de pim quinase n-{(7r)-4-[(3r,4r,5s)-3-amino-4-hidróxi-5-metilpiperidin-1-il]-7-hidróxi-6,7-di-hidro-5h-ciclopenta[b]piridin-3-il}-6-(2,6-difluorofe-nil)-5-fluoropiridina-2-carboxamida, incluindo métodos de preparação do mesmo, e intermediários na preparação do mesmo, em que o composto é útil no tratamento de doenças relacionadas a pim quinase, como câncer.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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