CORKEY Britton Kenneth,ELZEIN Elfatih,JIANG Robert H.,KALLA Rao V.,KOLTUN Dmitry,LI Xiaofen,MARTINEZ Ruben,PARKHILL Eric Q.,PERRY Thao,ZABLOCKI Jeff,VENKATARAMANI Chandrasekar,GRAUPE Michael,GUERRERO,M
申请号:
SI201231175
公开号:
SI2966067T1
申请日:
2012.06.29
申请国别(地区):
SI
年份:
2018
代理人:
摘要:
The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein Y, Z, n, R1 and R3 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.