Jinzhong Zhang,Keith W. Ward,Timothy L. Comstock,Dale W. Usner,Bruce A. Pfeffer,Mercedes Salvador-Silva,Charu A. DeWitt,Francisco J. Lopez,Claudio Bucolo
申请号：
US13245337
公开号：
US20120065228A1
申请日:
2011.09.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A composition for treating, controlling, reducing, or ameliorating inflammatory pain comprises a dissociated glucocorticoid receptor agonist (“DIGRA”), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester thereof. The composition can comprise an additional anti-inflammatory agent and can be formulated for topical application, injection, or implantation. It may be used in a method of managing ocular inflammation and/or pain such that it has lower risk of eliciting increased intraocular pressure seen with glucocorticoids.
