methods to delay the onset or slow progression of one or more symptoms, to delay the onset or progression of one or more symptoms, to identify an individual in need of a1pi maintenance therapy, and to identify individuals at high risk for exacerbations lungs, use of a1pi, apparatus and means for aerosolized administration of a1pi for inhalation, and

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专利权人:

GRIFOLS; S.A.

发明人:

Les Garlinghouse,Mark Forshag,Royce Waltrip,William Barnett

申请号：

BR112014007127

公开号：

BR112014007127A2

申请日:

2012.11.22

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

1/1 summary “methods to delay the onset or slow the progression of one or more symptoms, to delay the onset or progression of one or more symptoms, to identify an individual in need of therapy. maintenance, and to identify individuals at high risk for pulmonary exacerbations, use of a1pi, a1pi alpha 1-proteinase inhibitor to slow the onset or progression of pulmonary exacerbations. Methods are described herein to slow the onset or slow the progression of pulmonary exacerbations by administering inhaled alpha 1-proteinase inhibitor.1 / 1 resumo “mã‰todos para retardar o inã�cio ou diminuir a progressãƒo de um ou mais sintomas, para retardar o inã�cio ou a progressãƒo de um ou mais sintomas, para identificar um indivã�duo em necessidade de terapia de manutenã‡ãƒo de a1pi, e para identificar indivã�duos com risco elevado para exacerbaã‡ã•es pulmonares, uso de a1pi, aparelho e meio para a administraã‡ãƒo aerossolizada de a1pi para a inalaã‡ãƒo, e, kitâ€� inibidor da alfa 1-proteinase para retardar o inã­cio ou a progressã£o de exacerbaã§ãµes pulmonares. sã£o aqui descritos mã©todos para retardar o inã­cio ou diminuir a progressã£o de exacerbaã§ãµes pulmonares pela administraã§ã£o de inibidor da alfa 1-proteinase inalado.

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