A tissue clipping device (100) includes a capsule (106) extending from a proximal end to a distal end and including a lumen extending therethrough, a clip (102)including at least three arms (104) biased toward an open configuration and connected to one another at proximal ends thereof, the arms separated from one another circumferentially about a centerline of the clip and the proximal ends of the arms slidable within the lumen of the capsule to move the clip between the open configuration, in which distal ends of the arms are separated from one another to receive tissue therebetween and a closed configuration in which distal ends of the arms are moved toward one another to grip tissue in combination with a tension member (144) releasably coupling the clip to a proximal end of the device which remains accessible to a user, to control movement of the clip between the open and the closed configurations.
