compound, isolated enantiomer, pharmaceutical composition, method for inhibiting mct4 monocarboxylate transporter activity, or a mutant thereof, in a biological sample, method for inhibiting mct4 monocarboxylate transporter activity, or a mutant thereof, for mct1 monocarboxylate transporter, or mutant thereof, in a patient, method for treating a mct4 monocarboxylate transporter mediated disorder in a subject in need thereof, use of a compound and method to achieve an effect in a patient
Disclosed herein are compounds and compositions useful in the treatment of mct4-mediated diseases, such as inflammatory and proliferative diseases, which have the structure of formula i: (i) Methods for inhibiting mct4 activity in a human or animal subject are also provided. .são revelados no presente documento compostos e composições úteis no tratamento de doenças mediadas por mct4, como doenças inflamatórias e proliferativas, que têm a estrutura da fórmula i: (i) também são fornecidos métodos para inibição da atividade de mct4 em um sujeito humano ou animal.
