And so can be maintained in a sterile state of the needle point of the second needle tube until it punctures the chemical liquid storage portion which is filled with liquid medicine. Prefilled syringe 1 is provided with a liquid medicine containing portion 6 of the double-ended needle 3, the outer cylinder 2, a needle hub 4, the chemical solution M is Funyu, the pusher 5, and a cover member 17. The double-ended needle 3, the needle tip 9 having a first punctured in the living body is provided at one end, the needle tip 10 of the second chemical solution M is injected is provided at the other end. Holding the intermediate portion of the needle tube 3, the needle hub 4 is disposed so as to close the opening at one end of the outer cylinder 2. Also, the pusher 5 is operated so as to be movable in the axial direction of the outer cylinder 2 and the drug solution storage part 6. Then, the cover member 17, covering the needle tip 10 of the second side of the double-ended needle 3 which is exposed from the needle hub 4.薬液を封入した薬液収納部に穿刺するまで針管の第2の針先を無菌状態で維持することができるようにする。プレフィルドシリンジ1は、両頭針3と、外筒2と、針ハブ4と、薬液Mが舟生される薬液収納部6と、押し子5と、カバー部材17とを備えている。両頭針3は、生体に穿刺される第1の針先9が一端に設けられており、薬液Mが注入される第2の針先10が他端に設けられている。針ハブ4は、針管3の中間部を保持し、外筒2の一端側の開口を閉じるように配置されている。また、押し子5は、薬液収納部6を外筒2の軸方向に移動可能に操作する。そして、カバー部材17は、針ハブ4から露出している両頭針3のうち第2の針先10側を覆う。