#$%^&*AU2017258944B220181122.pdf#####ABSTRACT A mitral heart valve assembly system configured for staged implantation at a native mitral valve site via an endovascular access to a heart, comprising: an anchor assembly to implant along a native mitral valve annulus while the native mitral valve remains functional, the anchor assembly including: a supra-annular structure defining a first mating face at an upper portion of the anchor assembly configured to reside above the valve annulus of the native mitral valve； a plurality of wire structures extending downwardly away from the supraannular structure that are sized and shaped to extend through commissures between the native mitral valve leaflets and into a sub-annular position； and a plurality of subannular anchor feet connected to the wire structures that are sized and shaped to anchor into a sub-annular gutter along an underside of the valve annulus of the native mitral valve； and a valve assembly configured to subsequently mate with the anchor assembly after implantation of the anchor assembly, wherein the valve assembly includes: an occluder component having a plurality of leaflets positioned to occlude blood flow during systole and open to blood flow during diastole； a support component to maintain a portion of the occluder component in a supra-annular position above the valve annulus of the native mitral valve and further having a second mating face sized and shaped to be positioned inwardly of and directly mate with the first mating face of the supra-annular structure of the anchor assembly； and a lower peripheral portion that is sized and shaped to extend below the valve annulus of the native mitral valve while the support component maintains the portion of the occluder component in the supraannular position above the valve annulus.
