Meena Waleed Mahmood;Daniel Casciano;Alexandru S. Biris
发明人:
Alexandru S. Biris,Daniel Casciano,Meena Waleed Mahmood
申请号:
US13426154
公开号:
US09074187B2
申请日:
2012.03.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of inducing mineralization in a bone cell is described. The method comprises contacting a bone cell with a composition comprising nanoparticles. The nanoparticles can be single-walled carbon nanotubes, hydroxyapatite nanoparticles, TiO2 nanoparticles or silver nanoparticles. The bone cell can be an osteoblast cell. A method for increasing bone mass, bone healing or bone formation is also described which comprises administering to a subject in need thereof an effective amount of a composition comprising nanoparticles. The subject can suffer from a bone disease such as osteoporosis. The subject can suffer from a bone fracture and the method can comprise contacting bone cells near the bone fracture site with the composition. The composition can further comprise a pharmaceutically acceptable carrier.