Chimeric FVII-XTEN molecules and uses thereof

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专利权人:

Biogen MA Inc.

发明人:

Salas, Joe,Tan, Siyuan,Peters, Robert

申请号：

AU2014273881

公开号：

AU2014273881A1

申请日:

2014.05.30

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention provides chimeric FVII molecules comprising FVII, an XTEN polypeptide, and an antibody and antigen-binding molecules thereof which specifically bind the α and/or β subunits of the non-active form of the GPIIb/IIIIa receptor. The antibodies and antigen-binding molecules can be genetically fused and/or conjugated to heterologous moieties,

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