A method of optimizing the effectiveness of a medication for the treatment of a neurobehavioral or psychiatric disorder in a patient is presented. Medication is administered to a patient. Patient information is obtained and stored in a computer database. Real-time current information is received, for example from a mobile computer device, by the patient relating to (i) medication being taken by the patient； (ii) at least one benefit or lack of benefit of the medication to the patient； (iii) characteristics of one or more current tasks being performed by the patient； and (iv) a current condition of the patient. The effectiveness of the medication is evaluated based on stored patient information and received real-time current information. Accordingly, the dosage or frequency of the medication administered to the patient may be modified, eliminated or maintained.
