The present invention provides a mobile imaging system for imaging of patients in medical interventions comprising a ring gantry with a plurality of independently rotating rings whereas a first rotating ring positions an X-ray source with collimator and a second rotating ring positions an image detector such that the region of interest (patient) can be positioned off-centered with respect to the ring center. The system supports planar X-ray imaging and Computed Tomography (CT) and Cone beam CT (CBCT) acquisitions of three dimensional (3D) volumes with variable X-ray field of views (FOVs) adapted to regions of interest (ROIs), which are not required to be of cylindrical shape. The mobile system can be equipped with stereoscopic cameras integrated in the gantry an on moving rings to support optical tracking and navigation of instruments within the same co-ordinate system of X-ray information. The gantry can be equipped with additional sensors and robotic manipulators on further rings operating in said co-ordinate system on mobile platform. The gantry provides a generic mechanical and electrical interface to a supporting structure, which can be attached to a variety of mobility platforms to support robotic positioning of the system in various orientations of scanner in treatment rooms to accommodate a wide range of patient setups, including the possibility for inclined and vertical scans of patients in upright position.
