PROBLEM TO BE SOLVED: To provide a composition effective for the prevention and treatment of dementia, improving "the membrane transport of neurocytes" and "the vector transport function of ion, water and small molecules of astrocytes" by suppressing the decrease of ATP production, and further, maintaining the homeostasis of extracellular electrolytes by improving brain blood flow.SOLUTION: At least one kind of crude medicine corresponding to a body fluid utilization-improving medicine, a body moisture-controlling medicine or a blood-activating medicine, further a mixture containing at least one kind of the crude medicine corresponding to the body fluid utilization-improving medicine or body moisture-controlling medicine and at least one kind of the crude medicine corresponding to the blood activating medicine, and the Chinese/crude medicine containing the mixture are provided. The crude medicines corresponding to the body fluid utilization-improving medicine or body moisture-controlling medicine are Poria cocos sclerolium, Atractylodes rhizome, A. lanceae rhizome, Polyporus sclerolium, Alismatis rhizome, Stephania root, Coix seed, etc. The blood-activating medicines are Angerica sinensis root, Cnidii rhizome, Prunus persica seed, Curcuma zedoaria rhizome, Safflower, yakumoso, Coydalis tuber, Salvia miltiorrhizae root, Panax ginseng, Peony, Sparganium root tuber, Angles, Boswellia resin, Curcuma longa root, Dalbergia root core, Curcumas rhizome, Caesalpenia core, Panax notoginseng, Ginkgo biloba, Vinca minor, Rhdiola sacra, etc. The Chinese medicines are Kami-kihi-to, Yokukan-san-chinpi-hange, etc.COPYRIGHT: (C)2012,JPO&INPIT【課題】ATP産生低下を抑制することにより「神経細胞の膜輸送」、「アストロサイトのイオン・水・小分子のベクトル輸送機能」を向上させ、更に脳血流を改善して細胞外電解質の恒常性を維持することによる認知症の予防及び治療に有効な組成物の提供。【解決手段】利水薬若しくは化湿薬、或いは活血化お薬に該当する少なくとも1種の生薬、更に、利水薬または化湿薬に該当する少なくとも1種の生薬と活血化お薬に該当する少なくとも1種の生薬を含む混合物及びそれを含有する漢方・生薬製剤。利水薬若しくは化湿薬に該当する生薬が、茯苓、白朮、蒼朮、猪苓、沢瀉、防已、ヨクイニンなどである。活血化お薬が、当帰、川きゅう、桃仁、莪朮、紅花、益母草、延胡索、丹参、人参、芍薬、三りょう、莪朮、乳香、ウコン、降香、姜黄、蘇木、田七人参、
