Provided is a drug containing a novel active ingredient having a cancer immunity enhancing action, for inhibiting the progression of cancer, suppressing recurrence and / or treating cancer. The Allergin-1 antagonist according to the present invention has a cancer immunity enhancing action and can be used for inhibiting the progression of cancer, suppressing recurrence and / or treating cancer. In particular, it is useful for cancer treatment for cancer patients who are not sufficiently effective by treated with tumor immunotherapeutic drugs or for cancer treatment by combination with anti-cancer drugs.本發明之課題為提供一種以癌之進行抑制、再發抑制及/或治療為目的之藥劑,其包含具有癌免疫增強作用之新穎有效成分。根據本發明之過敏反應素-1拮抗劑具有癌免疫增強作用,可使用於癌之進行抑制、再發抑制及/或治療。尤其,在以腫瘤免疫治療藥之治療效果不充分之癌患者為對象的治療上、或在藉由與抗癌劑併用而進行之癌治療上有用。