Provided is a novel MRSA infection protective agent. Bacteria belonging to the genus Enterococcus have been found to be capable of protecting against MRSA infection. The MRSA infection protective agent comprises a bacterium belonging to the genus Enterococcus. Also provided are: a medicine for protection against MRSA infection, comprising a bacterium belonging to the genus Enterococcus; and a food for protection against MRSA infection, comprising a bacterium belonging to the genus Enterococcus.