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Quaternary ammonium diphenylmethyl compounds useful as muscarinic receptor antagonists
专利权人:
Christopher Lange;YuHua Ji;YongQi Mu;Craig Husfeld;Rick Lee
发明人:
YuHua Ji,Craig Husfeld,Christopher Lange,Rick Lee,YongQi Mu
申请号:
US12898858
公开号:
US08592453B2
申请日:
2010.10.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides compounds of formula I:in salt or zwitterionic form or a pharmaceutically acceptable salt thereof, wherein R1-6, a-e and Q are as defined in the specification. These compounds are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes for preparing such compounds and methods of using such compounds to, for example, treat pulmonary disorders such as chronic obstructive pulmonary disease and asthma.
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