TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE;ALTIF LABORATORIES, INC.
发明人:
申请号：
EP06833313.7
公开号：
EP1961816B1
申请日:
2006.11.17
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present invention provides, as an enzyme which can be used for enzyme replacement therapy for Fabry disease, a protein having ±-galactosidase activity, which shows no allergic adverse side effect, shows a high stability in blood, and can be easily incorporated into a cell of an affected organ. The protein of the present invention is a protein which has acquired ±-galactosidase activity by changing the structure of the active site of wild-type human ±-N-acetylgalactosaminidase.
