THE INVENTION RELATED TO COMPOUNDS OF FORMULA (I), WHEREIN THE SUBSTITUENS ARE AS DEFINED IN THE SPECIFICATION, IN FREE FORM OR IN THE FORM OF A PHARMACEUTICALLY ACCEPTABLE SALT, SOLVATE, ESTER, N-OXIDE THEREOF; PROCESSES FOR THE PREPARATION THEREOF; TO PHARMACEUTICALS CONTAINING SUCH COMPOUNDS, IN PARTICULAR FOR THE USE IN ONE OR MORE PROTEIN TYROSINE KINASE MEDIATED DISEASES.