Microparticles that include a charged polysaccharide (e.g., alginate) and an antimicrobial agent (e.g., chlorhexidine), along with related compositions and methods. The microparticles and related compositions can provide antimicrobial properties. Methods for manufacturing such microparticles, along with methods for applying the resulting microparticles to a substrate, such as a medical device or dressing, are also disclosed.
