DENG, LIANG,YANG, NING,MERGHOUB, TAHA,WOLCHOK, JEDD D.,SHUMAN, STEWART
申请号：
CA3081347
公开号：
CA3081347A1
申请日:
2018.11.06
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The technology of the present disclosure relates to the use of Heat-inactivated modified vaccinia Ankara (MVA) virus (Heat-iMVA) or Heat-inactivated vaccinia virus as a vaccine immune adjuvant. In particular, the present technology relates to the use of Heat-iMVA as a vaccine adjuvant for tumor antigens in cancer vaccines alone or in combination with immune checkpoint blockade (ICB) antibodies for use as a cancer immunotherapeutic.
