This invention relates to Supersaturated Self Nano Emulsifying Drug Delivery System (S-SNEDDS) for lipophilic drug. More particularly the invention S-SNEDDS comprising preconcentrates of oil, surfactant, co-surfactant and Polymer Precipitation Inhibitor (PPI). This invention inhibits the precipitation of Tamoxifen Citrate by maintaining supersaturated state in-vivo.