POMPER, MARTIN GILBERT,MEASE, RONNIE CHARLES,CHEN, YING
申请号:
PL09803670
公开号:
PL2318366T3
申请日:
2009.07.31
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.