The present invention provides a pharmaceutical composition comprising (S)-(3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl)methanol or a salt thereof for use in a method of treating a condition in a mammal selected from ischemic neuropathy, optic neuropathy, corneal pain, a retinal degenerative condition, skin erythema (redness) and inflammation, rosacea and acne.