METHOD FOR PRODUCING PENTAMERIC CRP, PENTAMERIC CRP-PRODUCING TRANSGENIC SILKWORM AND METHOD FOR CONSTRUCTING SAME, DNA ENCODING CANINE MONOMERIC CRP AND EXPRESSION VECTOR CONTAINING DNA
PROBLEM TO BE SOLVED: To provide a method for producing pentamer CRP by a genetic engineering technique highly efficiently.SOLUTION: Pentameric CRP is produced at a high efficiency by transferring DNA, which encodes monomeric CRP, into a silkworm to thereby construct a transgenic silkworm and then collecting and purifying pentameric CRP that is produced by the constructed transgenic silkworm.SELECTED DRAWING: Figure 2COPYRIGHT: (C)2016,JPO&INPIT【課題】5量体CRPを遺伝子工学的な手法により高効率で製造する製造方法を提供する。【解決手段】単量体CRPをコードするDNAをカイコに導入して遺伝子組換えカイコを作成し、次いで、作成した遺伝子組換えカイコが製造する5量体CRPを回収・精製することで、5量体CRPを高効率で製造する。【選択図】図2