A jaw closure mechanism for use in a surgical clip applier having first andsecondjaws movable relative to one another between a spaced-apart position and anapproximated position to form a surgical clip about tissue. The jaw closuremechanismincludes first and second eccentric wheels rotatably coupled to the respectivefirst andsecond jaws. Each of the wheels includes a center and a pivot point that isoffsetrelative to the center. A cable is disposed about each of the wheels. Thecable isengaged to the first wheel at a first engagement point and to the second wheelat asecond engagement point such that, upon application of a drive force to thecable, thewheels are rotated and displaced relative to the respective jaws from a firstposition to asecond position to urge the jaws from the spaced-apart position to theapproximatedposition.
