Use of 2-carboxamide cycloamino urea derivatives in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target EGFR family members
Saskia Maria BRACHMANN,Christine FRITSCH,Saveur-Michel MAIRA,Christian Renee SCHNELL,Carlos Garcia-Echeverria
申请号:
US16573909
公开号:
US20200022967A1
申请日:
2019.09.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The use of compounds of formula (I)in the treatment of Epidermal Growth Factor Receptor (EGFR) dependent diseases or diseases that have acquired resistance to agents that target EGFR family members, use of said compounds for the manufacture of pharmaceutical compositions for the treatment of said diseases, combinations of said compounds with EGFR modulators for said use, methods of treating said diseases with said compounds and pharmaceutical preparations for the treatment of said diseases comprising said compounds alone or in combination, especially with an EGFR modulator.