CNS gene delivery using peripheral administration of AAV10 vectors

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专利权人:

发明人:

申请号：

EP12172848.9

公开号：

EP2514827A1

申请日:

2008.07.22

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention relates to compositions and methods for the delivery of therapeutic proteins to the CNS using recombinant AAV 10 vectors. More specifically, the invention relates to compositions and methods for delivering proteins into the cerebrospinal fluid of mammalian subjects through peripheral administration of AAV10 vectors. The invention may be used to treat various disorders of the central nervous system, including degenerative diseases and motor neuron diseases.

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中国工程科技知识中心

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http://www.ckcest.cn/home/