There is provided topical pharmaceutical formulations comprising montelukast, or a pharmaceutically acceptable salt of solvate thereof, as well as combination products comprising (a) at least one mussel adhesive protein or a derivative thereof； and (b) montelukast, or a pharmaceutically-acceptable salt or solvate thereof. The formulations and combination products find particular utility in direct topical administration for the treatment of inflammation, of inflammatory disorders and/or of condition characterized by inflammation, including wounds, burns, psoriasis, acne and atopic dermatitis.本申請提供了包含孟魯司特或其醫藥上可接受的鹽或溶劑化物的局部醫藥調配物，以及包含(a)至少一種貽貝黏著蛋白或其衍生物和(b)孟魯司特或其醫藥上可接受的鹽或溶劑化物的組合產品。所述調配物和組合產品可特別用於直接局部投予，以治療炎症、炎症性病症和/或特徵在於炎症的病況，包括傷口、燒傷、牛皮癬、痤瘡和異位性皮膚炎。
