The present invention provides a synergistic herbicidal composition comprising Pyroxasulfone and Thifensulfuron methyl as the active components, as well as the use of the synergistic herbicidal composition of present invention for controlling the growth of undesirable plants. The present invention also provides a method of controlling the growth of undesirable plants, which comprises applying the active components Pyroxasulfone and Thifensulfuron methyl of the synergistic herbicidal composition of present invention to the undesirable plants or their growing locus jointly or separately. The present invention further provides a method of reducing or preventing harm caused by Pyroxasulfone when applied to plants, seeds or other reproductive parts of useful crops.