Gavin P. Robertson,Arati K. Sharma,Arun K. Sharma,Shantu G. Amin,Dhimant H. Desai
申请号：
US13785778
公开号：
US09126911B2
申请日:
2013.03.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation.
