ARGININE DEIMINASE WITH REDUCED CROSS-REACTIVITY TOWARD ADI - PEG 20 ANTIBODIES FOR CANCER TREATMENT

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专利权人:

POLARIS GROUP;SHOWALTER, RICHARD

发明人:

ALMASSY, ROBERT,THOMSON, JAMES A.,SHOWALTER, RICHARD,SISSON, WES,SHIA, WEI-JONG,CHEN, LI-CHANG,LEE, YANG

申请号：

SG11201702103X

公开号：

SG11201702103XA

申请日:

2015.09.16

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.

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中国工程科技知识中心

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http://www.ckcest.cn/home/