Rhoda Myra Alani,Philip A. Cole,Gai Yan,Erin M. Bowers
申请号：
US13520619
公开号：
US09005670B2
申请日:
2011.01.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides methods for treating cancer comprising inhibiting the activity of p300/CBP histone acetyltransferase (HAT). Also provided are p300/CBP HAT inhibitors for treating a subject having cancer. In addition, the present invention includes biomarkers for p300/CBP HAT inhibition, which are used to i) monitor the effectiveness of cancer therapy, and ii) identify anti-cancer agents for use in combination therapy.
