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ORALLY DISINTEGRATING COATED TABLET
专利权人:
TORAY INDUSTRIES; INC.
发明人:
TAKAKI, SUGURU,OHTA, KOTOE,HORIUCHI, YASUHIDE
申请号:
EP10758612
公开号:
EP2415466A4
申请日:
2010.03.29
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to a stable orally disintegrating coated tablet containing a drug, wherein the tablet is coated with a coating layer containing a water-soluble substance and a polyvinyl alcohol resin of not less than 5% by weight based on the weight of the coating layer, the water-soluble substance dissolving in an amount of 1 g or more in less than 10 mL of water at 20°C, having a hydroxyl group(s) in its molecule, and having a molecular weight of not more than 200 per a unit hydroxyl group. There is provided a stable orally disintegrating coated tablet which does not cause a crack in the coating layer even when the orally disintegrating tablet has been swollen by moisture absorption under high humidity, while ensuring rapid disintegration properties in an oral cavity. In the case of an orally disintegrating tablet containing a light-unstable drug, degradation of the drug can be suppressed by blending a light shading agent in the coating layer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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