OPTIMIZED EARLY-LATE PROMOTER COMBINED WITH REPEATED VACCINATION FAVORS CYTOTOXIC T CELL RESPONSE AGAINST ANTIGENS IN REPLICATION DEFICIENT RECOMBINANT VIRUS VACCINES

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专利权人:

Bavarian Nordic A/S

发明人:

Brinkmann, Kay,Baur, Karen,Hausmann, Jürgen,Steigerwald, Robin,Dirmeier, Ulrike

申请号：

AU2015203893

公开号：

AU2015203893A1

申请日:

2015.07.10

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

#$%^&*AU2015203893A120150806.pdf#####Abstract The present invention relates to a replication deficient recombinant virus encoding at least one antigen and/or antigenic epitope, wherein expression of said antigen and/or 5 antigenic epitope is regulated by a transcriptional control element comprising at least two elements driving early expression of said antigen and/or antigenic epitope and the use of said replication deficient recombinant virus as medicament or vaccine. 51

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